Chimera genetics12/28/2022 This results in the development of an organism with intermingled cell lines. This condition occurs through the fertilization of two separate ova by two sperm, followed by the fusion of the two at the blastocyst or zygote stages. Tetragametic chimerism is a form of congenital chimerism. Chimeras can often breed, but the fertility and type of offspring depends on which cell line gave rise to the ovaries or testes varying degrees of intersexuality may result if one set of cells is genetically female and another genetically male. The likelihood of offspring being a chimera is increased if it is created via in vitro fertilization. In nonidentical twins, chimerism occurs by means of blood-vessel anastomoses. This condition is either inherited, or it is acquired through the infusion of allogeneic hematopoietic cells during transplantation or transfusion. Chimeras are typically seen in animals there are some reports on human chimerism. Each population of cells keeps its own character and the resulting organism is a mixture of tissues. Chimeras are formed from four parent cells (two fertilized eggs or early embryos fused together). If the different cells have emerged from the same zygote, the organism is called a mosaic. A chimera or chimaera is a single organism (usually an animal) that is composed of two or more different populations of genetically distinct cells that originated from different zygotes involved in sexual reproduction.
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